Buy Paroxetine Online
Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.
Sertraline is used to treat depression, obsessive-compulsive disorder, anxiety disorders (including panic disorder and social anxiety disorder), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).
For the management of major depressive disorder (MDD),Paroxetine posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD),Paroxetine panic disorder (PD) with or without agoraphobia, premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD)
It may be used for premature ejaculation and vascular headaches as off-label indications.
Paroxetine Sertraline, an antidepressant drug similar to citalopram, fluoxetine, and paroxetine, is of the selective serotonin reuptake inhibitor (SSRI) type. Sertraline has one active metabolite and, like the other SSRIs, have less sedative, anticholinergic, and cardiovascular effects than the tricyclic antidepressant drugs because it does not have clinically important anticholinergic, antihistamine, or adrenergic (alpha1, alpha2, beta) blocking activity.
In vitro, Paroxetine sertraline has no significant affinity for GABA, dopaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors. It mediates a weak inhibitory actions on the neuronal uptake of norepinephrine or dopamine and exhibits no inhibitory action on monoamine oxidase.
The pharmacological role of sigma receptors in the mechanism of action of sertraline is unclear.
The exact mechanism of action sertraline is not fully known, but the drug appears to selectively inhibit the reuptake of serotonin at the presynaptic membrane. This results in an increased synaptic concentration of serotonin in the CNS, which leads to numerous functional changes associated with enhanced serotonergic neurotransmission.
Paroxetine it is suggested that these modifications are responsible for the antidepressant action observed during long term administration of antidepressants. It has also been hypothesized that obsessive-compulsive disorder is caused by the dysregulation of serotonin, as it is treated by sertraline, and the drug corrects this imbalance.
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